Antiproliferative Activities of Cynaropicrin and Related Compounds against Cancer Stem Cell
Kousuke Araki, Minami Hara, Shohei Hamada, Takahiro Matsumoto, Seikou Nakamura
Chemical & Pharmaceutical Bulletin 72(2) 200-208 2024年2月20日
2023年度
論文
Production of dihydroisocoumarins by callus induction from Hydrangea macrophylla var. thunbergii leaves
Junko Tsukioka, Tomoka Takami, Yuki Ario, Seikou Nakamura
Chemical & Pharmaceutical Bulletin 71(11) 832-837 2023年11月1日
Cytotoxic activities of alkaloid constituents from the climbing stems and rhizomes of Sinomenium acutum against cancer stem cells
Masaya Okayama, Takahiro Matsumoto, Takahiro Kitagawa, Seikou Nakamura, Tomoe Ohta, Tatsusada Yoshida, Tetsushi Watanabe
Journal of Natural Medicines 78(1) 226-235 2024年1月31日
Quantitative analysis of taxiphyllin, a cyanogenic glycoside, in the leaves of Hydrangea macrophylla var. thunbergii
Junko Tsukioka, Yutaro Ohki, Momona Nakao, Seikou Nakamura
Journal of Natural Medicines 77(4) 978-985 2023年9月30日
Dual Chalcogen-Bonding Interactions for the Conformational Control of Urea
Takumi Inoue, Moe Ota, Yui Amijima, Haru Takahashi, Shohei Hamada, Seikou Nakamura, Yusuke Kobayashi, Takahiro Sasamori,Takumi Furuta
Chemistry - A European Journal 29(60) e202302139 2023年10月26日
Antiproliferative activities of diterpenes from leaves of Isodon trichocarpus against cancer stem cells
Seikou Nakamura, Sachiko Sugimoto, Taichi Yoneda, Akari Shinozaki, Moe Yoshiji, Takahiro Matsumoto, Souichi Nakashima, Hisashi Matsuda
Chemical & Pharmaceutical Bulletin 71(7) 502-507 2023年7月1日
Comparison of growth in Hydrangea macrophylla var. thunbergii grown in different soil pH and quantitative analysis of its sweetness-related constituents
Junko Tsukioka, Seikou Nakamura
Chemical & Pharmaceutical Bulletin 71(5) 368-373 2023年5月1日
総説
Development of functional compounds using chemically unstable compounds obtained from medicinal plants
Seikou Nakamura
Yakugaku Zasshi 144(1) 21-26 2024年1月
New biofunctional effects of oleanane-type triterpene saponins
Hisashi Matsuda, Toshio Morikawa, Seikou Nakamura, Osamu Muraoka, Masayuki Yoshikawa
Journal of Natural Medicines 77(4) 644-664 2023年9月30日
2022年度
論文
Plantainoside B in Bacopa monniera Binds to Aβ Aggregates Attenuating Neuronal Damage and Memory Deficits Induced by Aβ
Aina Fukuda, Souichi Nakashima, Yoshimi Oda, Kaneyasu Nishimura, Hidekazu Kawashima, Hiroyuki Kimura, Takashi Ohgita, Eri Kawashita, Keiichi Ishihara, Aoi Hanaki, Mizuki Okazaki, Erika Matsuda, Yui Tanaka, Seikou Nakamura, Takahiro Matsumoto, Satoshi Akiba, Hiroyuki Saito, Hisashi Matsuda, Kazuyuki Takata
Biological & Pharmaceutical Bulletin 46(2) 320-333 2023年2月1日
One-pot synthesis of carbazoles by a domino reaction using microwave heating and antiproliferative activities of constituents from Murraya plants against cancer stem cells
Kouta Ugawa, Momona Nakao, Chikako Sawada, Takahiro Matsumoto, Takahiro Kitagawa, Yutaro Ohki, Kousuke Araki, Seikou Nakamura
Heterocycles 106(4) 725-733 2023年2月28日
7,8-Dihydroxy-3-(4'-hydroxyphenyl)coumarin inhibits invasion and migration of osteosarcoma cells
Yuki Sugiyama, Seikou Nakamura, Yuichi Tokuda, Masakazu Nakano, Yasunao Hattori, Hiroki Nishiguchi, Yuki Toda, Shigekuni Hosogi, Masayuki Yamashita, Kei Tashiro, Eishi Ashihara
Biochemical and Biophysical Research Communications 638 200-209 2023年1月1日
Effects of piperine, a component of pepper (Piper nigrum), on herpes simplex virus type-1 in Vero cells
Seikou Nakamura, Tomoyo Namura, Yuka Nishimura
Journal of Asian Association of Schools of Pharmacy 11 1-5 2022年9月1日
Analysis of Active Compounds Using Target Protein Cofilin-Cucurbitacins in Cytotoxic Plant Bryonia cretica
Souichi Nakashima, Yoshimi Oda, Moeko Morita, Ayako Ohta, Toshio Morikawa, Hisashi Matsuda, Seikou Nakamura
Toxins 14(3) 2022年3月16日
Chemical Structures of Phenylbutanoids From Rhizomes of Zingiber cassumunar
Seikou Nakamura, Junko Iwami, Yutana Pongpiriyadacha, Souichi Nakashima, Hisashi Matsuda, Masayuki Yoshikawa
Natural Product Communications 17(2) 1934578X2210778-1934578X2210778 2022年2月23日
Construction of sulfur-containing compounds with anti-cancer stem cell activity using thioacrolein derived from garlic based on nature-inspired scaffolds
Taichi Yoneda, Naoto Kojima, Takahiro Matsumoto, Daisuke Imahori, Tomoe Ohta, Tatsusada Yoshida, Tetsushi Watanabe, Hisashi Matsuda, Seikou Nakamura
Organic & Biomolecular Chemistry 20(1) 196-207 2022年12月2日
Synthesis of 1-methoxy-1H-indoles with a heterocyclic moiety via unstable indole isothiocyanate by using enzyme from Brassicaceae plant
Kaori Ryu, Seikou Nakamura, Koya Miyagawa, Souichi Nakashima, Hisashi Matsuda
Heterocycles 103(1) 416-424 2021年7月1日
Estrogenic and antiandrogenic activities of methoxyflavans isolated from the fruit of Mauritia flexuosa (Moriche Palm)
Kenchi Miyasaka, Shogo Takeda, Seikou Nakamura, Hisashi Matsuda, Hiroshi Shimoda
Journal of Food Biochemistry 45(1) e13583 2020年12月19日
One-pot enantioselective synthesis of (S)-spirobrassinin and non-natural (S)-methylspirobrassinin from amino acids using a turnip enzyme
Kaori Ryu, Seikou Nakamura, Souichi Nakashima, Hisashi Matsuda
Journal of Natural Medicines 75(2) 308-318 2021月1月3日
Inhibitory effects of cynaropicrin and related sesquiterpene lactones from leaves of artichoke (Cynara scolymus L.) on induction of iNOS in RAW264.7 cells and its high-affinity proteins
Tomoko Matsumoto, Souichi Nakashima, Seikou Nakamura, Yasunao Hattori, Tomoshige Ando, Hisashi Matsuda
Journal of Natural Medicines 75(2) 381-392 2021年1月23日
Detection of new 3,4-dimethylpyrrole derivatives upon the incubation of exogenous amines with extract of onion (Allium cepa) and crude alliinase from garlic (A. sativum)
Taichi Yoneda, Seikou Nakamura, Shogo Okui, Sayaka Okazaki, Souichi Nakashima, Hisashi Matsuda
Heterocycles 102(11) 2168-2178 2021月9月7日
Effective search of triterpenes with anti-HSV-1 activity using a classification model by logistic regression.
Keiko Ogawa, Seikou Nakamura, Haruka Oguri, Kaori Ryu, Taichi Yoneda, Rumiko Hosoki
Frontiers in Chemistry 9 763794 2021年11月2日
総説
Sulfur-containing compounds from leaves of Allium plants, A. fistulosum, A. schoenoprasum var. foliosum, and A. sativum
Seikou Nakamura, Souichi Nakashima, Hisashi Matsuda
Journal of Asian Association of Schools of Pharmacy 10 1-8 2021年