主な研究業績




※2016年以前の業績は各教員のプロフィールからご覧ください。

  • 2024年

    • 1.　Katsuya Morito, Mayu Yamagata, Futaba Naka, Kayo Kobayashi, Hikari Ueda, Hirotoshi Morimoto, Takeshi Yasukawa, Kentaro Takayama, Yoshinobu Uozumi, Kazuki Nagasawa. Sub-chronic and mild social defeat stress exposure to C57BL/6J mice increases visceral fat mass and causes accumulation of cholesterol and bile acids in the liver. Biochem. Biophys. Res. Commun., 702: 149631, 2024. https://doi.org/10.1016/j.bbrc.2024.149631
    • 2.　Asuka Nomoto, Yui Suzuki, Katsuya Morito, Kazuki Nagasawa, Kentaro Takayama. Suppressive effects of neuromedin U receptor 2-selective peptide agonists on appetite and prolactin secretion in mice. ACS Med. Chem. Lett., 15: 376-380, 2024. https://doi.org/10.1021/acsmedchemlett.3c00541
    • 3.　Utano Tanaka, Keisuke Mogi, Natsumi Fujita, Miho Moriwake, Katsuya Morito, Kentaro Takayama, Hirotoshi Morimoto, Takeshi Yasukawa, Yoshinobu Uozumi, Kazuki Nagasawa. Alteration of sweet and bitter taste sensitivity with development of glucose intolerance in non-insulin-dependent diabetes mellitus model OLETF rats. Biol. Pharm. Bull., 47: 739-749, 2024. https://doi.org/10.1248/bpb.b23-00756
    •  

    2023年

    1.　Katsuya Morito, Ryota Shimizu, Hanif Ali, Akina Shimada, Tohru Miyazaki, Naoko Takahashi, M Motiur Rahman, Kazuki Tsuji, Nobuyuki Shimozawa, Michiyasu Nakao, Shigeki Sano, Momoyo Azuma, Meera Nanjundan, Kentaro Kogure, Tamotsu Tanaka. Molecular species profiles of plasma ceramides in different clinical types of X-linked adrenoleukodystrophy. J. Med. Invest., 70: 403-410, 2023. https://doi.org/10.2152/jmi.70.403
  • 2.　Kenjiro Matsumoto, Mayu Kamide, Kunitoshi Uchida, Mitsuki Takahata, Runa Shichiri, Yuka Hida, Yumi Taniguchi, Akihiro Ohishi, Makoto Tominaga, Kazuki Nagasawa, Shinichi Kato. Transient receptor potential ankyrin 1 in taste nerve contributes to the sense of sweet taste in mice. Biol. Pharm. Bull., 46: 939-945, 2023. https://doi.org/10.1248/bpb.b23-00091
  • 3.　Minagi Mukaiyama, Chihiro Uchiyama, Akane Fukuda, Yoshiki Nakazawa, Yuka Kuramochi, Yudai Shibata, Sho Konno, Kyohei Muguruma, Naohiro Matsugaki, Tomo Asari, Kazuyoshi Ogawa, Akihiro Taguchi, Kentaro Takayama, Atsuhiko Taniguchi, Yoko Nagumo, Toshiya Senda, Yoshio Hayashi, Takeo Usui. X-ray conformation and structure-activity relationships of MA026, a reversible tight junction opener. J. Med. Chem., 66: 8717-8724, 2023. https://doi.org/10.1021/acs.jmedchem.3c00365
  • 4.　Hayate Shida, Akihiro Taguchi, Sho Konno, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi. Establishment of one-pot disulfide-driven cyclic peptide synthesis with a 3-nitro-2-pyridinesulfenate. Chem. Pharm. Bull., 71: 435-440, 2023. https://doi.org/10.1248/cpb.c23-00087
  • 5.　Kohki Michiue, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi, Kentaro Kogure. Increasing skeletal muscle mass in mice by non-invasive intramuscular delivery of myostatin inhibitory peptide by iontophoresis. Pharmaceuticals, 16: 397, 2023. https://doi.org/10.3390/ph16030397
  • 6.　Hideyuki Okamoto, Shuko Amber Murano, Kaoru Ikekawa, Masahiro Katsuyama, Sho Konno, Akihiro Taguchi, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi. Inactivation of myostatin by photooxygenation using functionalized D-peptides. RSC Med. Chem., 14: 386392, 2023. https://doi.org/10.1039/d2md00425a
  • 7.　Hanif Ali, Miyu Kobayashi, Katsuya Morito, Rumana Yesmin Hasi, Mutsumi Aihara, Junji Hayashi, Ryushi Kawakami, Koichiro Tsuchiya, Kazunori Sango, Tamotsu Tanaka. Peroxisomes attenuate cytotoxicity of very long-chain fatty acids. Biochim. Biophys. Acta, 1868: 159259, 2023. https://doi.org/10.1016/j.bbalip.2022.159259
  •  

2022年　

  • 1.　S. M. Khaledur Rahman, Zahir Hussain, Katsuya Morito, Naoko Takahashi, Mohammad Mamun Sikder, Tamotsu Tanaka, Ken-Ichi Ohta, Masaki Ueno, Hiroo Takahashi, Tohru Yamamoto, Makoto Murakami, Toru Uyama, Natsuo Ueda. Formation of N-acyl-phosphatidylethanolamines by cytosolic phospholipase A2ε in an ex vivo murine model of brain ischemia. Biochim. Biophys. Acta, 1867: 159222, 2022. https://doi.org/10.1016/j.bbalip.2022.159222
  • 2.　Kentaro Nishida, Saho Bansho, Akiko Ikukawa, Teruyo Kubota, Akihiro Ohishi, Kazuki Nagasawa. Expression profile of the zinc transporter ZnT3 in taste cells of rat circumvallate papillae and its role in zinc release, a potential mechanism for taste stimulation. Eur. J. Histochem., 66: 3534, 2022. https://doi.org/10.4081/ejh.2022.3534
  • 3.　Tamotsu Tanaka, Kazuya Koyama, Naoko Takahashi, Katsuya Morito Hanif Ali, Momoyo Azuma, Kozo Kagawa, Hiroshi Kawano, Rumana Yesmin Hasi, Mutsumi Aihara, Yasuhiko Nishioka. Lysophosphatidic acid, ceramide 1-phosphate and sphingosine 1-phosphate in peripheral blood of patients with idiopathic pulmonary fibrosis. J. Med. Invest., 69: 196-203,2022. https://doi.org/10.2152/jmi.69.196
  • 4.　Junjiro Yoshida, Kentaro Takayama, Manabu Kawada. Short peptides derived from hGAPDH exhibit anti-cancer activity. Bioorg. Med. Chem., 71: 116953, 2022. https://doi.org/10.1016/j.bmc.2022.116953
  • 5.　Kako Hanada, Kunpei Fukasawa, Hinata Hiroki, Shú Imai, Kentaro Takayama, Hideyo Hirai, Rina Ohfusa, Yoshio Hayashi, Fumiko Itoh. Combination therapy of anamorelin with a myostatin inhibitor is advantageous for cancer cachexia in a mouse model. Cancer Sci., 113: 3547-3557 2022. https://doi.org/10.1111/cas.15491
  • 6.　Yuka Takahata,Waka Yoshimoto, Eri Kuwagaki, Yukie Yamada, Kazuki Nagasawa. Alteration of sweet taste receptor expression in circumvallate papillae of mice with decreased sweet taste preference induced by social defeat stress. J. Nutr. Biochem., 107: 109055, 2022. https://doi.org/10.1016/j.jnutbio.2022.109055
  • 7.　Kayo Miyanaga, Ayumi Asada, Miki Komoto, Yasuyuki Ohshima, Hirotoshi Morimoto, Takeshi Yasukawa, Ruka Matsuura, Katsuya Morito, Kentaro Takayama, Yoshinobu Uozumi, Kazuki Nagasawa. Prophylactic administration of magnesium oxide prevents dextran sulfate sodium-induced colonic injury in mice. Biol. Pharm. Bull., 45: 1312-1320, 2022. https://doi.org/10.1248/bpb.b22-00278
  • 8.　Kentaro Takayama. Peptide tool-driven functional elucidation of biomolecules related to endocrine system and metabolism. Chem. Pharm. Bull., 70: 413-419, 2022. https://doi.org/10.1248/cpb.c22-00048
  • 9.　Yan Cui, Akihiro Taguchi, Hayate Shida, Sho Konno, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi. Chemical synthesis of an HIV-1 protease analog with some amides in a polypeptide main chain replaced by disulfide bonds. Bull. Chem. Soc. Jpn., 95: 1156-1162, 2022. https://doi.org/10.1246/bcsj.20220103
  • 10.　Kentaro Takayama, Keisuke Hitachi, Hideyuki Okamoto, Mariko Saitoh, Miki Odagiri, Rina Ohfusa, Takahiro Shimada, Akihiro Taguchi, Atsuhiko Taniguchi, Kunihiro Tsuchida, Yoshio Hayashi. Development of myostatin inhibitory D-peptides to enhance the potency, increasing skeletal muscle mass in mice. ACS Med. Chem. Lett., 13: 492-498, 2022. https://doi.org/10.1021/acsmedchemlett.1c00705
  • 11.　Hanif Ali, Katsuya Morito, Rumana Yesmin Hasi, Mutsumi Aihara, Junji Hayashi, Ryushi Kawakami, Kaori Kanemaru, Koichiro Tsuchiya, Kazunori Sango, Tamotsu Tanaka. Characterization of uptake and metabolism of very long-chain fatty acids in peroxisome-deficient CHO cells. Biochim. Biophys. Acta, 1867: 159088, 2022. https://doi.org/10.1016/j.bbalip.2021.159088
  • 12.　Miki Komoto, Ayumi Asada, Yasuyuki Ohshima, Kayo Miyanaga, Hirotoshi Morimoto, Takeshi Yasukawa, Katsuya Morito, Kentaro Takayama, Yoshinobu Uozumi, Kazuki Nagasawa. Dextran sulfate sodium-induced colitis in C57BL/6J mice increases their susceptibility to chronic unpredictable mild stress that induces depressive-like behavior.Life Sci., 289: 120217, 2022. https://doi.org/10.1016/j.lfs.2021.120217

 

2021年

  • 1.　Keisuke Mogi, Ikumi Kamiya, Aimi Makino, Ayaka Hirao, Reina Abe, Yusuke Doi, Taro Shimizu, Hidenori Ando, Katsuya Morito, Kentaro Takayama, Tatsuhiro Ishida, Kazuki Nagasawa. Liposomalization of oxaliplatin exacerbates the non-liposomal formulation-induced decrease of sweet taste sensitivity in rats. J. Pharm. Sci., 110: 3937-3945, 2021. https://doi.org/10.1016/j.xphs.2021.07.004
  • 2.　Yusuke Kamimura, Erina Kuwagaki, Sakika Hamano, Mami Kobayashi, Yukie Yamada, Yuka Takahata, Waka Yoshimoto, Hirotoshi Morimoto, Takeshi Yasukawa, Yoshinobu Uozumi, Kazuki Nagasawa. Reproducible induction of depressive-like behavior in C57BL/6J mice exposed to chronic social defeat stress with a modified sensory contact protocol. Life Sci., 282: 119821, 2021. https://doi.org/10.1016/j.lfs.2021.119821
  • 3.　Mariko Saitoh, Kentaro Takayama, Yoshimi Roppongi, Takahiro Shimada, Akihiro Taguchi, Atsuhiko Taniguchi, Yoshio Hayashi. Strategic structure–activity relationship study on a follistatin-derived myostatin inhibitory peptide. Bioorg. Med. Chem. Lett., 46: 128163, 2021. https://doi.org/10.1016/j.bmcl.2021.128163
  • 4.　Kyohei Muguruma, Rento Ohsawa, Akane Fukuda, Naoto Ishikawa, Konomi Fujita, Akihiro Taguchi, Kentaro Takayama, Atsuhiko Taniguchi, Yuji Ito, Yoshio Hayashi. Development of a high-affinity antibody-binding peptide for site-specific modification. ChemMedChem, 16: 1813-1820, 2021. https://doi.org/10.1002/cmdc.202000977
  • 5.　Tomo Asari, Hiroaki Ikeyama, Akihiro Taguchi, Atsuhiko Taniguchi, Yoshio Hayashi, Kentaro Takayama. Proposal for the binding mode of the 23-mer inhibitory peptide to myostatin. Bioorg. Med. Chem., 40: 116181, 2021. https://doi.org/10.1016/j.bmc.2021.116181
  • 6.　Chihiro Uchiyama, Akane Fukuda, Minagi Mukaiyama, Yoshiki Nakazawa, Yuka Kuramochi, Kyohei Muguruma, Mitsue Arimoto, Akihiro Ninomiya, Koichiro Kako, Yohei Katsuyama, Sho Konno, Akihiro Taguchi, Kentaro Takayama, Atsuhiko Taniguchi, Yoko Nagumo, Takeo Usui, Yoshio Hayashi. Structural revision of natural cyclic depsipeptide MA026 established by total synthesis and biosynthetic gene cluster analysis. Angew. Chem. Int. Ed., 60: 8792-8797, 2021. https://doi.org/10.1002/ange.202015193
  • 7.　田中保, 森戸克弥. 食事あるいは腸内細菌に由来する非動物型脂肪酸の代謝. 甲南大学総合研究所叢書, 141: 31-46, 2021.
  • 8.　Hanif Ali, Ryouhei Yamashita, Jun-ichi Morishige, Katsuya Morito, Naoya Kakiuchi, Junji Hayashi, Mutsumi Aihara, Ryushi Kawakami, Koichiro Tsuchiya, Tamotsu Tanaka. Mass spectrometric analysis of sphingomyelin with N-α-hydroxy fatty acyl residue in mouse tissues. Lipids, 56: 181-188, 2021. https://doi.org/10.1002/lipd.12285
  • 9.　Kiyotaka Kobayashi, Akihiro Taguchi, Yan Cui, Hayate Shida, Kyohei Muguruma, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi. “On-resin” disulfide peptide synthesis with methyl 3-nitro-2-pyridinesulfenate. Eur. J. Org. Chem., 2021: 956-963, 2021. https://doi.org/10.1002/ejoc.202001517
  • 10.　Hideyuki Okamoto, Atsuhiko Taniguchi, Shoya Usami, Masahiro Katsuyama, Sho Konno, Akihiro Taguchi, Kentaro Takayama, Yoshio Hayashi, Development of functionalized peptides for efficient inhibition of myostatin by selective photooxygenation. Org. Biomol. Chem., 19: 199-207, 2021. https://doi.org/10.1039/D0OB02042G

 

2020年

  • 1.　森戸克弥, 田中保. ペルオキシソームにおける脂肪酸酸化の役割. 生化学, 92: 632-639, 2020. https://doi.org/10.14952/SEIKAGAKU.2020.920632
  • 2.　Midori Fukui, Toshihiko Tsutsumi, Aimi Yamamoto-Mikami, Katsuya Morito, Naoko Takahashi, Tamotsu Tanaka, Takeshi Iwasa, Akira Kuwahara, Minoru Irahara, Akira Tokumura. Distinct contributions of two choline-producing enzymatic activities to lysophosphatidic acid production in human amniotic fluid from pregnant women in the second trimester and after parturition. Prostaglandins Other Lipid Mediat., 150: 106471, 2020. https://doi.org/10.1016/j.prostaglandins.2020.106471
  • 3.　Rumana Yesmin Hasi, Dai Majima, Katsuya Morito, Hanif Ali, Kentaro Kogure, Meera Nanjundan, Junji Hayashi, Ryushi Kawakami, Kaori Kanemaru, Tamotsu Tanaka. Isolation of glycosylinositol phosphoceramide and phytoceramide 1-phosphate in plants and their chemical stabilities. J. Chromatogr. B, 1152: 122213, 2020. https://doi.org/10.1016/j.jchromb.2020.122213
  • 4.　Toshihiko Tsutsumi, Risa Matsuda, Katsuya Morito, Kohei Kawabata, Miho Yokota, Miki Nikawadori, Manami Inoue-Fujiwara, Satoshi Kawashima, Mayumi Hidaka, Takenori Yamamoto, Naoshi Yamazaki, Tamotsu Tanaka, Yasuo Shinohara, Hiroyuki Nishi, Akira Tokumura. Identification of human glycerophosphodiesterase 3 as an ecto phospholipase C that converts the G protein-coupled receptor 55 agonist lysophosphatidylinositol to bioactive monoacylglycerols in cultured mammalian cells. Biochim. Biophys. Acta, 1865: 158761, 2020. https://doi.org/10.1016/j.bbalip.2020.158761
  • 5.　Kentaro Takayama, Kenji Mori, Tomo Asari, Yuko Sohma, Erina Nomura, Yu Sasaki, Akihiro Taguchi, Atsuhiko Taniguchi, Mikiya Miyazato, Naoto Minamino, Kenji Kangawa, Yoshio Hayashi. Design and synthesis of peptidic partial agonists of human neuromedin U receptor 1 with enhanced serum stability. Bioorg. Med. Chem. Lett., 30: 127436, 2020. https://doi.org/10.1016/j.bmcl.2020.127436
  • 6.　Yan Cui, Akihiro Taguchi, Kiyotaka Kobayashi, Hayate Shida, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi. Use of solid-supported 4-fluorophenyl 3-nitro-2-pyridinesulfenate in construction of disulfide-linked hybrid molecules. Org. Biomol. Chem., 18: 7094-7097, 2020. https://doi.org/10.1039/D0OB01370F
  • 7.　Chiharu Ojima, Yuri Noguchi, Tatsuki Miyamoto, Yuki Saito, Hiroki Orihashi, Yasuhiro Yoshimatsu, Tetsuro Watabe, Kentaro Takayama, Yoshio Hayashi, Fumiko Itoh. Peptide-2 from mouse myostatin precursor protein alleviates muscle wasting in cancer-associated cachexia. Cancer Sci., 111: 2954-2964, 2020. https://doi.org/10.1111/cas.14520
  • 8.　髙山健太郎. マウス由来マイオスタチン阻害ペプチドの構造活性相関研究. PEPTIDE NEWSLETTER JAPAN. 117:, 8-10, 2020. https://www.peptide-soc.jp/files/newsletter/PNJ117.pdf
  • 9.　Guillaume Vares, Vincent Jallet, Yoshitaka Matsumoto, Cedric Rentier, Kentaro Takayama, Toshio Sasaki, Yoshio Hayashi, Hiroaki Kumada, Hirotaka Sugawara. Functionalized mesoporous silica nanoparticles for innovative boron-neutron capture therapy of resistant cancers. Nanomedicine. 27: 102195, 2020. https://doi.org/10.1016/j.nano.2020.102195
  • 10.　Kentaro Takayama, Miki Odagiri, Akihiro Taguchi, Atsuhiko Taniguchi, Yoshio Hayashi. Enzymatic stability of myostatin inhibitory 16-mer peptides. Chem. Pharm. Bull., 68: 512-515, 2020. https://doi.org/10.1248/cpb.c20-00158
  • 11.　Kentaro Takayama, Kenji Mori, Akiko Tanaka, Yu Sasaki, Yuko Sohma, Akihiro Taguchi, Atsuhiko Taniguchi, Toshiyasu Sakane, Akira Yamamoto, Mikiya Miyazato, Naoto Minamino, Kenji Kangawa, Yoshio Hayashi. A chemically stable peptide agonist to neuromedin U receptor type 2. Bioorg. Med. Chem., 28: 115454, 2020. https://doi.org/10.1016/j.bmc.2020.115454
  • 12.　Moemi Iwamura, Risa Honda, Kazuki Nagasawa. Elevation of the blood glucose level is involved in an increase in expression of sweet taste receptors in taste buds of rat circumvallate papillae. Nutrients, 12: 990, 2020. https://doi.org/10.3390/nu12040990
  • 13.　Akihiro Taguchi, Kiyotaka Kobayashi, Yan Cui, Kentaro Takayama, Atsuhiko Taniguchi, Yoshio Hayashi. Disulfide-driven cyclic peptide synthesis of human endothelin-2 with a solid-supported Npys-Cl. J. Org. Chem., 85: 1495-1503, 2020. https://doi.org/10.1021/acs.joc.9b02362
  • 14.　Mariko Saitoh, Kentaro Takayama, Keisuke Hitachi, Akihiro Taguchi, Atsuhiko Taniguchi, Kunihiro Tsuchida, Yoshio Hayashi. Discovery of a follistatin-derived myostatin inhibitory peptide. Bioorg. Med. Chem.Lett., 30: 126892, 2020. https://doi.org/10.1016/j.bmcl.2019.126892
  • 15.　Akiko Tanaka, Kentaro Takayama, Tomoyuki Furubayashi, Kenji Mori, Yuki Takemura, Mayumi Amano, Chiaki Maeda, Daisuke Inoue, Shunsuke Kimura, Akiko Kiriyama, Hidemasa Katsumi, Mikiya Miyazato, Kenji Kangawa, Toshiyasu Sakane, Yoshio Hayashi, Akira Yamamoto. Transnasal delivery of the peptide agonist specific to neuromedin-U receptor 2 to the brain for the treatment of obesity. Mol. Pharm., 17: 32-39, 2020. https://doi.org/10.1021/acs.molpharmaceut.9b00571

 

2019年

  • 1.　Takahiro Furuta, Akihiro Ohishi, Kazuki Nagasawa. Intracellular labile zinc is a determinant of vulnerability of cultured astrocytes to oxidative stress. Neurosci. Lett., 707: 134315, 2019. https://doi.org/10.1016/j.neulet.2019.134315
  • 2.　Kenjiro Matsumoto, Akihiro Ohishi, Ken Iwatsuki, Kaho Yamazaki, Satoko Takayanagi, Masahiro Tsuji, Eitaro Aihara, Daichi Utsumi, Takuya Tsukahara, Makoto Tominaga, Kazuki Nagasawa, Shinichi Kato. Transient receptor potential vanilloid 4 mediates sour taste sensing via type III taste cell differentiation. Sci. Rep., 9: 6686, 2019. https://doi.org/10.1038/s41598-019-43254-y
  • 3.　Keiichi Ishihara, Eri Kawashita, Ryohei Shimizu, Kazuki Nagasawa, Hiroyuki Yasui, Haruhiko Sago, Kazuhiro Yamakawa, Satoshi Akiba. Copper accumulation in the brain causes the elevation of oxidative stress and less anxious behavior in Ts1Cje mice, a model of Down syndrome. Free Radic. Biol. Med., 134: 248-259, 2019. https://doi.org/10.1016/j.freeradbiomed.2019.01.015

 

2018年

  • 1.　大石晃弘, 長澤一樹. 抗がん剤による味覚障害. ファルマシア, 54: 1060-1064, 2018. https://doi.org/10.14894/faruawpsj.54.11_1060
  • 2.　Kentaro Nishida, Kazuya Takeuchi, Ayami Hosoda, Shohei Sugano, Eri Morisaki, Akihiro Ohishi, Kazuki Nagasawa. Ergothioneine ameliorates oxaliplatin-induced peripheral neuropathy in rats. Life Sci., 207: 516-524, 2018. https://doi.org/10.1016/j.lfs.2018.07.006
  • 3.　Kentaro Nishida, Yuka Nomura, Kanako Kawamori, Akihiro Ohishi, Kazuki Nagasawa. ATP metabolizing enzymes ENPP1, 2 and 3 are localized in sensory neurons of rat dorsal root ganglion. Eur. J. Histochem., 62: 2877, 2018. https://doi.org/10.4081/ejh.2018.2877

 

2017年

  • 1.　Kentaro Nishida, Misaki Kashiwagi, Shunsuke Shiba, Kiwamu Muroki, Akihiro Ohishi, Yusuke Doi, Hidenori Ando, Tatsuhiro Ishida, Kazuki Nagasawa. Liposomalization of oxaliplatin induces skin accumulation of it, but negligible skin toxicity. Toxicol. Appl. Pharmacol., 337: 76-84, 2017. https://doi.org/10.1016/j.taap.2017.10.006
  • 2.　Takahiro Furuta, Ayumi Mukai, Akihiro Ohishi, Kentaro Nishida, Kazuki Nagasawa. Oxidative stress-induced increase of intracellular zinc in astrocytes decreases their functional expression of P2X7 receptors and engulfing activity. Metallomics, 9: 1839-1851, 2017. https://doi.org/10.1039/c7mt00257b
  • 3.　Kenshi Ohbori, Makiko Fujiwara, Akihiro Ohishi, Kentaro Nishida, Yoshinobu Uozumi, Kazuki Nagasawa. Prophylactic oral administration of magnesium ameliorates dextran sulfate sodium-induced colitis in mice through a decrease of colonic accumulation of P2X7 receptor-expressing mast cells. Biol. Pharm. Bull., 40: 1071-1077, 2017. https://doi.org/10.1248/bpb.b17-00143
  • 4.　Akihiro Koike, Jyakusho Sou, Akihiro Ohishi, Kentaro Nishida, Kazuki Nagasawa. Inhibitory effect of divalent metal cations on zinc uptake via mouse Zrt-/Irt-like protein 8 (ZIP8). Life Sci., 173: 80-85, 2017. https://doi.org/10.1016/j.lfs.2016.12.006
  • 5.　Akihiro Ohishi, Kentaro Nishida, Karin Miyamoto, Mizuka Imai, Ryoko Nakanishi, Kyoko Kobayashi, Akiko Hayashi, Kazuki Nagasawa. Bortezomib alters sour taste sensitivity in mice. Toxicol. Rep., 4: 172-180, 2017. https://doi.org/10.1016/j.toxrep.2017.03.003
  • 6.　Makiko Fujiwara, Kenshi Ohbori, Akihiro Ohishi, Kentaro Nishida, Yoshinobu Uozumi, Kazuki Nagasawa. Species difference in sensitivity of human and mouse P2X7 receptors to inhibitory effects of divalent metal cations. Biol. Pharm. Bull., 40: 375-380, 2017. https://doi.org/10.1248/bpb.b16-00887