Miho Hamai, Anju Ishii, Nozomi Sakamoto, Hiroki Fujioka, Junko Tsukioka, Tomoe Ohta, Seikou Nakamura, Takahiro Matsumoto. The endophyte secondary metabolite phenazine-1-carboxylic acid promotes tanshinone biosynthesis in Salvia miltiorrhiza callus. J. Nat. Med, 2026 in press.
Shogo Nishikawa, Ryuya Takada, Mahiro Nagabuchi, Ayana Nagano, Moe Nakamura, Yoshiaki Manse, Tomoe Ohta, Tatsusada Yoshida, Takahiro Matsumoto, Toshio Morikawa. Prenylflavonoids with antiallergic activity from the roots of Sophora flavescens Aiton. Phytochemistry, 252, 115049, 2026.
Haruka Kawatake, Sakura Ichioka, Yutaro Ohki, Kouta Ugawa, Masaya Mori, Miho Hamai, Chiho Shimadzu, Minami Hara, Tomoe Ohta, Hiromi Ii, Susumu Nakata, Takahiro Matsumoto, Seikou Nakamura. Development of karapinchamine A-related carbazoles with antiproliferative activity against glioblastoma-derived cancer stem cells and blood–brain barrier permeability. Bioorg. Med. Chem. Lett., 141, 130745, 2026.
Shogo Nishikawa, Ryuya Takada, Yusuke Shimomoto, Sara Morishita, Yoshiaki Manse, Tomoe Ohta, Tatsusada Yoshida, Takahiro Matsumoto, Toshio Morikawa. β-glucuronidase inhibitors isolated from the fruit of Forsythia suspensa (Thunb.) Vahl. J. Nat. Med, 2026 in press.
Masaya Mori, Hiromi Ii, Mai Matsumura, Yuhi Sone, Haruna Kumamoto, Kana Sakurai, Teruna Fujino, Nanami Nihei, Nana Hongo, Kozue Nose, Takahiro Matsumoto, Mitsugu Fujita, Susumu Nakata. Dual inhibition of xCT and GGCT induces ferroptosis in glioblastoma cells by depleting cysteine and disrupting redox homeostasis. Cell death discovery, 2026.
Hayato Yoshikawa, Emi Yoshida, Takahiro Matsumoto, Kazuma Sugita, Saki Kamiya, Takashi Ohgita, Shinji Kobuchi, Shun Shimohama, Kazuyuki Takata. Identification of daurioxoisoporphine D and moringamine I as blood–brain barrier–permeable natural inhibitors of amyloid-β aggregation and neuronal toxicity. Bioorganic and Medicinal Chemistry, 2026, 138 118664-118664.
Seikou Nakamura, Takahiro Matsumoto, Rie Yasui, Toshiki Minamide, Tomoe Ohta, Souichi Nakashima, Hisashi Matsuda. Constituents with dipeptidyl peptidase-IV inhibitory effect from the flower buds of Rosa rugosa. Journal of Asian Association of Schools of Pharmacy, 2026, 15(1) 1-5.
学会発表
Miho Hamai, Youhei Saito, Takahiro Matsumoto, Screening of compounds targeting heat shock protein-mediated bortezomib resistance for prevention of Multiple Myeloma cells recurrence, フォーラム2026 衛生薬学・環境トキシコロジー 日韓次世代シンポジウム, 東京 2026.8
Takahiro Matsumoto. Investigation and development of natural products that target chemotherapy resistance factors in cancer cells. J. Nat. Med., 2025, 79, 1005-1016.
Takahiro Matsumoto, Miho Hamai, Yayako Inui, Tomoe Ohta, Tatsusada Yoshida, Naoto Kojima, Hayato Yoshikawa, Raku Kutose, Shiori Ando, Tetsushi Watanabe. Chemical structures of polyketides and alkaloids isolated from a culture of fungus Curvularia moringae. Fitoterapia, 2024,179,106263.
Kousuke Araki, Minami Hara, Shohei Hamada, Takahiro Matsumoto, Seikou Nakamura. Antiproliferative Activities of Cynaropicrin and Related Compounds against Cancer Stem Cells. Chem. Pharm. Bull., 2024,72, 200-208.
Takahiro Kitagawa, Takahiro Matsumoto, Tomoe Ohta, Tatsusada Yoshida, Youhei Saito, Yuji Nakayama, Yuki Hadate, Eishi Ashihara, Tetsushi Watanabe. Linderapyrone analogue LPD-01 as a cancer treatment agent by targeting importin7 J. Nat. Med, 2024, 78, 370-381.
Takahiro Matsumoto, Erika Ohnishi, Masaya Okayama, Tomoe Ohta, Tatsusada Yoshida, Shiori Ando, Raku Kutose, Takahiro Kitagawa, Tetsushi Watanabe. Chemical structures and cell-death-inducing activities of metabolites produced by Penicillium maximae. Tetrahedron Lett., 2024, 134,154851-154851.
Masaya Okayama, Takahiro Matsumoto, Takahiro Kitagawa, Seikou Nakamura, Tomoe Ohta, Tatsusada Yoshida, Tetsushi Watanabe. Cytotoxic activities of alkaloid constituents from the climbing stems and rhizomes of Sinomenium acutum against cancer stem cells. J. Nat. Med, 2024, 78, 226-235.