PUBLICATIONS
PUBLICATIONS
2015
- Shinji Kobuchi, Yukako Ito, Taro Hayakawa, Asako Nishimura, Nobuhito Shibata, Kanji Takada, and Toshiyuki Sakaeda: Semi-physiological pharmacokinetic–pharmacodynamic (PK-PD) modeling and simulation of 5-fluorouracil for thrombocytopenia in rats. Xenobiotica, 45(1), 19-28 (2015).
2014
- Yukako Ito, Shinji Kobuchi, Yutaro Takemura, Miki Aoki, Marina Haruna, Toshiyuki Sakaeda, Kanji Takada: Prolonged hypoglycemic effects obtained by two-layered dissolving microneedles containing insulin glargine. J. Drug Del. Sci. Tech., 24, 601-606 (2014).
- Yukako Ito, Mayu Taniguchi, Asuka Hayashi, Miku Anai, Shinya Morita, Emi Ko, Naoko Yoshimoto, Yasuhiro Yoshi, Shinji Kobuchi, Toshiyuki Sakaeda, Kanji Takada: Application of dissolving microneedles to glucose monitoring through dermal interstitial fluid. Biol. Pharm. Bull., 37, 1776-1781 (2014).
- Shinji Kobuchi, Yukako Ito, Taro Hayakawa, Asako Nishimura, Nobuhito Shibata, Kanji Takada, and Toshiyuki Sakaeda: Pharmacokinetic–pharmacodynamic (PK-PD) modeling and simulation of 5-fluorouracil for erythropenia in rats. J. Pharmacol. Toxicol. Methods, 70, 134-144 (2014).
- Shinji Kobuchi, Yukako Ito, Taro Hayakawa, Shota Kuwano, Akiko Baba, Kota Shinohara, Asako Nishimura, Nobuhito Shibata, and Kanji Takada: Semi-physiological pharmacokinetic–pharmacodynamic modeling and simulation of 5-fluorouracil for the whole time course of alterations in leukocyte, neutrophil, and lymphocyte counts in rats. Xenobiotica, 44, 804-818 (2014).
- Tetsuya Minegaki, Akiko Kuwahara, Motohiro Yamamori, Tsutomu Nakamura, Tatsuya Okuno, Ikuya Miki, Hideaki Omatsu, Takao Tamura, Midori Hirai, Takeshi Azuma, Toshiyuki Sakaeda, Kohshi Nishiguchi. Genetic Polymorphisms in SLC23A2 as Predictive Biomarkers of Severe Acute Toxicities after Treatment with a Definitive 5-Fluorouracil/Cisplatin-Based Chemoradiotherapy in Japanese Patients with Esophageal Squamous Cell Carcinoma. Int. J. Med. Sci., 11, 321-326 (2014).
- Toshiyuki Sakaeda, Kaori Kadoyama, Keiko Minami, Yasushi Okuno: Commonality of Drug-associated Adverse Events Detected by 4 Commonly Used Data Mining Algorithms. Int. J. Med. Sci., 11, 461-465 (2014).
- Kyoko Seki, Yasuo Tsuduki, Takeshi Ioroi, Michiko Yamane, Hiroko Yamauchi, Yukinari Shiraishi, Tadaaki Ogawa, Izumi Nakata, Kohshi Nishiguchi, Teruhisa Matsubayashi, Yoshihide Takakubo, Motohiro Yamamori, Akiko Kuwahara, Noboru Okamura, Toshiyuki Sakaeda: Serum Lactate Dehydrogenase Levels as a Predictive Marker of Oxaliplatin-Induced Hypersensitivity Reactions in Japanese Patients with Advanced Colorectal Cancer. Int. J. Med. Sci., 11, 641-645 (2014).