Department of Pharmaceutical Chemistry
Kyoto Pharmaceutical University
京都薬科大学 創薬科学系 薬化学分野 
 

PUBLICATIONS 2016–2020

 
 
 

2020

 
 
 
 
Azolium/hydroquinone organo-radical co-catalysis: Aerobic C–C-bond cleavage in ketones
Nakatsuji, Y.; Kobayashi, Y.; Masuda, S,; Takemoto, Y.
Chem. Eur. J., Accepted Article. (DOI: 10.1002/chem.202004943)
 
 
 
近年のニトロキシル型酸化触媒の展開
浜田翔平、古田 巧
京都薬科大学紀要、2020年 第1巻 第2号 71–86
 
 
 
Regio- and Stereoselective Glycosylation of 1,2-O-unprotected Sugars Using Organoboron Catalysts
Kobayashi, Y.; Takemoto, Y.
Tetrahedron 76, 131328 (2020). (DOI: 10.1016/j.tet.2020.131328)
 
 
Chemoselective Oxidation of p-Methoxybenzyl Ethers by an Electronically Tuned Nitroxyl Radical Catalyst
Hamada, S.; Sugimoto, K.; Elboray, E. E.; Kawabata, T.; Furuta, T.
Org. Lett. 22, 5486–5490 (2020). (DOI: 10.1021/acs.orglett.0c01839)
 

 
 
Solvent-Dependent Mechanism and Stereochemistry of Mitsunobu Glycosylation with Unprotected Pyranoses
Takeuchi, H.; Fujimori, Y.; Ueda, Y.; Shibayama, H.; Nagaishi, M.; Yoshimura, T.; Sasamori, T.; Tokitoh, N.; Furuta, T.; Kawabata, T.
Org. Lett.22, 4754–4759 (2020). (DOI: 10.1021/acs.orglett.0c01549)
 
 
A Solvent-dependent Chirality-switchable Thia-Michael Addition to α,β-Unsaturated Carboxylic Acids using a Chiral Multifunctional Thiourea Catalyst
Hayama, N.; Kobayashi, Y.; Sekimoto, E.; Miyazaki, A.; Inamoto, K.; Kimachi, T.; Takemoto, Y.
Chem. Sci.11, 5572–5576 (2020). (DOI: 10.1039/D0SC01729A)
 
 
Stereoselective Synthesis of 1,1'-Disaccharides by Organoboron Catalysis
Izumi, S.; Kobayashi, Y.; Takemoto, Y.
Angew. Chem. Int. Ed., Early View. (DOI: 10.1002/anie.202004476)
 
 
Mild and Chemoselective Thioacylation of Amines Enabled by the Nucleophilic Activation of Elemental Sulfur
Saito, M.; Murakami, S.; Nanjo, T.; Kobayashi, Y.; Takemoto, Y.
J. Am. Chem. Soc. 142, 8130–8135 (2020). (DOI: 10.1021/jacs.0c03256)
 
 
Reactions Catalyzed by 2-Halogenated Azolium Salts: From Halogen-Bond Donors to Brønsted-Acidic Salts
Kobayashi, Y.; Takemoto, Y.
Synlett, 31, 772–783 (2020). (DOI: 10.1055/s-0039-1690815)
 
 
Photo-Irradiation-Promoted Aminoetherification of Glycals with N-Acyliminoiodinane and Alcohols
Masakado, S.; Kobayashi, Y.; Takemoto, Y.
Heterocycles, 101, 453–460 (2020). (DOI: 10.3987/COM-19-S(F)25)
 
 
Axial Chirality in N,N-Dialkylaminopyridine Derivatives Bearing an Internal Carboxy Group
Nishino, R.; Hamada, S.; Elboray, E. E.; Ueda, Y.; Kawabata, T.; Furuta, T.
Chirality, 32, 588–593 (2020). (DOI: 10.1002/chir.23207)
 

 
 
Synthesis of Axially Chiral Binaphthothiophene delta-Amino Acid Derivatives Bearing Chalcogen Bonds
Hamada, S.; Wang, S.; Murai, T.; Xing, Y.; Inoue, T.; Ueda, Y.; Sasamori, T.; Kawabata, T.; Furuta, T.
Heterocycles, 101, 328–338 (2020). (DOI: 10.3987/COM-19-S(F)15)

 
 
 

2019

 
Simple and Rapid p-Methoxybenzylation of Hydroxy and Amide Groups at Room Temperature by NaOt-Bu and DMSO
Hamada, S.; Sugimoto, K.; Iida, M.; Furuta, T.
Tetrahedron Lett., 60, 151277 (2019). (DOI: 10.1016/j.tetlet.2019.151277).
 

 
 
Chrysin enhances anticancer drug-induced toxicity mediated by the reduction of claudin-1 and 11 expression in a spheroid culture model of lung squamous cell carcinoma cells
Murahashi, R.; Eguchi, H.; Akizuki, R.; Hamada, S.; Furuta, T.; Matsunaga, T.; Endo, S.; Ichihara, K.; Ikari, A.
Sci. Rep. 9, 13753 (2019). (DOI: 10.1038/s41598-019-50276-z)
 
 
Synthesis of 4-Deoxy Pyranoside via Catalyst-Controlled Site-Selective Toluoylation of Abundant Sugars
Yanagi, M.; Ueda, Y.; Ninomiya, R.; Imayoshi, A.; Furuta, T.; Mishiro, K.; Kawabata, T.
Org. Lett. 21, 5006–5009 (2019). (DOI: 10.1021/acs.orglett.9b01549)
 
 
Synthesis and Biochemical Characterization of Quasi-Stable Trimer Models of Full-Length Amyloid β40 with A Toxic Conformation
Irie, Y.; Hanaki, M.; Murakami, K.; Imamoto, T.; Furuta, T.; Kawabata, T.; Kawase, T.; Hirose, K.; Minobe, Y.; Akagi, K.; Yanagita, R. C.; Irie, K.
Chem. Commun. 55, 182–185 (2019). (DOI: 10.1039/C8CC08618D)
 

2018
 

Synthesis and Structural Properties of Axially Chiral Binaphthothiophene Dicarboxylic Acid
Murai, T.; Xing, Y.; Kuribayashi, T.; Lu, W.; Guo, J.-D.; Yella, R.; Hamada, S.; Sasamori, T.; Tokitoh, N.; Kawabata, T.; Furuta, T.
Chem. Pharm. Bull. 66, 1203–1206 (2018). (DOI: 10.1248/cpb.c18-00668).
 

 
 
Biaryl Amino Acids and Their Surrogates: A Unique Class of Unnatural Amino Acid
Furuta, T.
"Designed Molecular Space in Material Science and Catalysis" (Ed: Shirakawa, S.), Springer, 123–145 (2018). (DOI: 10.1007/978-981-13-1256-4_6)
 

 
 
Design and Synthesis of Biaryl Amino Acids and Related Catalysts with Molecular Recognition Properties

Furuta, T.
J. Syn. Org. Chem. Jpn., 2, 1188–1191 (2018). (DOI: 10.1059/yukigoseikyokaishi.76.122)
 

 
 

2017

 

Asymmetric Intramolecular C-H Insertion Promoted by Dirhodium(II) Carboxylate Catalyst Bearing Axially Chiral Amino Acid Derivatives

Lu, W.; Pei, X.; Murai, T.; Sasamori, T.; Tokitoh, N.; Kawabata, T.; Furuta, T.
Synlett, 28, 679–683 (2017). (DOI: 10.1055/s-0036-1588674)
 

 

 
 

2016

 
Catalytic Discrimination Between Formyl Groups in Regio- and Stereoselective Intramolecular Cross–Aldol Reactions
Baba, T.; Yamamoto, J.; Hayashi, K.; Sato, M.; Yamanaka, M.; Kawabata, T.; Furuta, T.
Chem. Sci., 7, 3791–3797 (2016). (DOI: 10.1039/C5SC04594K)